Laboratory measurement of neurotransmitters and hormones for Sanesco's CSM clinical model are performed by NeuroLab, the foremost reference laboratory for the measurement of biomarkers relative to HPA-T axis function. Click here to learn more about NeuroLab. The test menu below gives practitioners options for assessing patients key neurotransmitters and adrenal function together or independently.

Test Menu:

HPA Profile: (Hypothalamus/Pituitary/Adrenal)

Provides measurement of 6 primary urinary neurotransmitters: Serotonin, GABA, Glutamate, Dopamine, Norepinephrine, Epinephrine. Salivary Adrenal Hormones are also measured: 4 timed Cortisols and 2 DHEAs.

This profile assesses the six neurotransmitters that affect the hypothalamic-pituitary axis (HP) as well as the adrenal hormones cortisol and DHEA. Since the HPA axis initiates an adrenal response, this profile allows the practitioner to assess that response and make therapeutic decisions based on the information. Neurotransmitters are measured from a single urine sample, while cortisol (X4) and DHEA (X2) are measured from four saliva samples, the first taken between 7:00 and 8:00 am and then one every five hours thereafter for the remaining three samples.

HP Profile: (Hypothalamus/Pituitary)

Provides measurement of 6 primary urinary Neurotransmitters: Serotonin, GABA, Glutamate, Dopamine, Norepinephrine, Epinephrine

The HP (hypothalamic-pituitary) Profile analyzes the six main neurotransmitters involved in HP axis function. The major inhibitory and excitatory neurotransmitters are included to determine the degree of balance or imbalance in the neurotransmitter response of the Communication System. The HP Profile requires one urine sample, taken two to three hours after rising, usually between 8:00 and 10:00 am.

AH Profile: (Adrenal Hormones)

Provides measurement of salivary Adrenal Hormones: 4 timed cortisols and 2 DHEAs

The AH (adrenal hormone) Profile analyzes cortisol levels at four times during the day, allowing the practitioner to graph the patient's curve against a normal adrenal curve. The circadian rhythm of adrenal tissue is best assessed at multiple times of the day to determine the adrenal gland's ability to respond to daily stressors and therapeutic intervention. Cortisol (X4) and DHEA (X2) levels are measured from four saliva samples, the first collected between 7:00 and 8:00 am and then one every five hours thereafter for the remaining three samples.

Customized profiles may be ordered. Options are available to allow the practitioner to choose from one to six neurotransmitter tests and either two cortisol levels or two cortisols and one DHEA. This option is most commonly used to retest during monitoring of the therapeutic/clinical response. Please contact a Practice Building Specialist to discuss custom profile options.